Anti-PP2C alpha antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | PP2C alpha |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500); Immunohistochemistry (1:60-1:200); Immunocytochemistry (1:80-1:500); Flow Cytometry (1:60-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Protein phosphatase 2C isoform alpha antibody |
| EC 3.1.3.16 antibody | |
| FLJ42306 antibody IA antibody | |
| MGC9201 antibody | |
| Mpp alpha antibody | |
| PP2C alpha antibody | |
| PP2C-alpha antibody | |
| PP2CA antibody | |
| PP2Calpha antibody | |
| PPM 1A antibody | |
| PPM1A antibody | |
| PPM1A_HUMAN antibody | |
| PPPM1A antibody | |
| Protein phosphatase 1A (formerly 2C) magnesium dependent alpha isoform antibody | |
| Protein phosphatase 1A antibody | |
| Protein phosphatase 1A magnesium dependent alpha antibody | |
| Protein phosphatase 2C alpha antibody | |
| Protein phosphatase 2C alpha isoform antibody | |
| Protein phosphatase 2C isoform alpha antibody | |
| Protein phosphatase IA antibody |
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Target information
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Provider
Erpantech Laboratory