Anti-Complement C3（β- chain） antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Complement C3(β chain) |
| Immunogen: | Peptide |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:2000); Flow Cytometry; Immunocytochemistry |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (11-10) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 2mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Acylation-stimulating protein cleavage product antibody |
| AHUS5 antibody | |
| ARMD9 antibody | |
| ASP antibody | |
| C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody | |
| C3 antibody | |
| CO3_HUMAN antibody | |
| Complement C3 antibody | |
| Complement C3 beta chain antibody | |
| Complement C3c alpha' chain fragment 2 antibody | |
| Complement component 3 antibody | |
| Complement component C3 antibody | |
| Complement factor 3 antibody | |
| CPAMD1 antibody |
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Target information
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Provider
Erpantech Laboratory