Anti-CRTC3 antibody
Specifications
| Product Cat#: | AB-06-1174 |
| Product type: | Primary antibody |
| Antigen: | CRTC3 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:2000); Immunocytochemistry (1:100-1:500); Immunohistochemistry (1:100-1:500) |
| Reactivity: | Human, Monkey |
| Clonality (clone number): | Monoclonal (G8-A9) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CREB regulated transcription coactivator 3 antibody |
| CREB-regulated transcription coactivator 3 antibody | |
| CRTC 3 antibody | |
| CRTC3 antibody | |
| CRTC3_HUMAN antibody | |
| FLJ21868 antibody | |
| TORC 3 antibody | |
| TORC-3 antibody | |
| TORC3 antibody | |
| Transducer of CREB protein 3 antibody | |
| Transducer of regulated cAMP response element binding protein (CREB) 3 antibody | |
| Transducer of regulated cAMP response element binding protein 3 antibody |
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Target information
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ‘Ser-133’ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Provider
Erpantech Laboratory