Anti-NeuroD1 antibody
Specifications
| Product Cat#: | AB-06-3096 |
| Product type: | Primary antibody |
| Antigen: | NeuroD1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:2000);Immunoprecipitation |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal(JM11-10) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | atonal antibody |
| basic helix loop helix transcription factor antibody | |
| BETA 2 antibody | |
| Beta cell E box transactivator 2 antibody | |
| BETA2 antibody | |
| BHF 1 antibody | |
| BHF1 antibody | |
| bHLHa3 antibody | |
| class A basic helix loop helix protein 3 antibody | |
| Class A basic helix-loop-helix protein 3 antibody | |
| MODY 6 antibody |
Target information
The basic helix-loop-helix (bHLH) proteins are transcription factors that are required for several aspects of development, including cell type determination, terminal differentiation and sex determination. The HLH domain is required for dimerization, while the basic region makes specific contacts with DNA. Members of the myogenic determination family, MyoD, myf5, myogenin and MRF4, all have bHLH domains. These proteins heterodimerize with members of the E protein family and initiate myogenesis. Neuro D has been identified as a bHLH transcription factor functioning in neurogenic differentiation. Neuro D is expressed transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation into mature neurons. Moreover, ectopic expression of Neuro D in Xenopus embryos induces premature differentiation of neuronal precursors and Neuro D can convert presumptive epidermal cells into neurons.
Provider
Erpantech Laboratory
