Anti-ZNF281 antibody
Specifications
| Product Cat#: | AB-06-4710 |
| Product type: | Primary antibody |
| Antigen: | ZNF281 |
| Immunogen: | KLH conjugated synthetic peptide derived from Human ZNF281 802-895/895 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10mM Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Zfp281 |
| GC box binding zinc finger protein 1 | |
| GC-box-binding zinc finger protein 1 | |
| GZP1 | |
| Transcription factor ZBP-99 | |
| ZBP 99 | |
| ZBP99 | |
| zfp281 | |
| Zinc finger DNA binding protein 99 | |
| Zinc finger DNA-binding protein 99 | |
| Zinc Finger Protein 281 | |
| ZN281_HUMAN | |
| ZNF281 | |
| ZNP 99 | |
| ZNP 99 transcription factor |
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Target information
Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.
Provider
Erpantech Laboratory