Anti-WDR26 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | WDR26 |
| Immunogen: | KLH conjugated synthetic peptide derived from human WDR26 101-200/514 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot(1:450-1:2000); Immunohistochemistry-Paraffin(1:450-1:800); Flow Cytometry (1) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Cow, Horse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Myocardial ischemic preconditioning upregulated protein 2 |
| WDR26 | |
| PRO0852 | |
| CDW2 | |
| MIP2 | |
| CUL4 and DDB1 associated WDR protein 2 | |
| Myocardial ischemic preconditioning up regulated protein 2 | |
| Myocardial ischemic preconditioning upregulated protein 2 | |
| WD repeat domain 26 | |
| WD repeat-containing protein 26 | |
| FLJ21016 |
Target information
G-beta-like protein involved in cell signal transduction . Acts as a negative regulator in MAPK signaling pathway. Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes . Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 . Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubiquitination of beta-catenin CTNNB1 by the beta-catenin destruction complex, thus negatively regulating CTNNB1 degradation . Serves as a scaffold to coordinate PI3K/AKT pathway-driven cell growth and migration . Protects cells from oxidative stress-induced apoptosis via the down-regulation of AP-1 transcriptional activity as well as by inhibiting cytochrome c release from mitochondria . Protects also cells by promoting hypoxia-mediated autophagy and mitophagy (By similarity).
Provider
Erpantech Laboratory