Anti-CD108 antibody
Specifications
| Product Cat#: | AB-06-0833 |
| Product type: | Primary antibody |
| Antigen: | CD108 |
| Immunogen: | KLH conjugated synthetic peptide derived from human Sema7A 351-450/666 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:800-1:2000 ); Immunohistochemistry-Paraffin ( 1:500-800 ) |
| Reactivity: | Mouse, Rat, Dog, Cow and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.03 % Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Semaphorin 7A |
| CD 108 | |
| CD108 | |
| CD108 Antigen | |
| CDw108 | |
| H Sema K1 | |
| H Sema L | |
| JMH | |
| JMH Blood GroupAntigen | |
| John Milton Hagen Blood Group H Sema K1 | |
| John Milton Hargen Human Blood Group Ag | |
| MGC126692 | |
| MGC126696 | |
| Sema Domain Immunoglobulin Domain (Ig) and GPI Membrane Anchor 7A | |
| Sema L | |
| Sema7a | |
| SEMAK1 | |
| SEMAL | |
| Semaphorin 7A GPI Membrane Anchor | |
| Semaphorin K1 | |
| Semaphorin L | |
| Semaphorin7a |
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Target information
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Provider
Erpantech Laboratory