Anti-WASL antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | WASL |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry(1:40-1:200); Immunocytochemistry (1:40-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (JU07-31) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | WASP family, verprolin homology domain-containing protein 1 antibody |
| WASP family member 1 antibody | |
| FLJ31482 antibody | |
| Homology of dictyostelium scar 1 antibody | |
| KIAA0269 antibody | |
| Protein WAVE-1 antibodyv Protein WAVE1 antibody | |
| Scar, Dictyostelium, homology of, 1 antibody | |
| SCAR1 antibody | |
| Similar to a plant extensin like protein antibody | |
| Verprolin homology domain containing protein 1 antibody | |
| Verprolin homology domain-containing protein 1 antibody | |
| WAS protein family, member 1 antibody | |
| Wasf1 antibody | |
| WASF1_HUMAN antibody | |
| WASL antibody | |
| WASP family 1 antibody | |
| WASP family protein member 1 antibody | |
| WASP family, verprolin homology domain-containing protein antibody | |
| WAVE antibody | |
| WAVE1 antibody | |
| Wiskott Aldrich syndrome protein family member 1 antibody | |
| Wiskott-Aldrich syndrome protein family member 1 antibody |
Target information
Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex . Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization . Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia . In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization . Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression (By similarity). Plays a role in dendrite spine morphogenesis (By similarity). Decreasing levels of DNMBP (using antisense RNA) alters apical junction morphology in cultured enterocytes, junctions curve instead of being nearly linea.
Provider
Erpantech Laboratory