Anti-WAS antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | WAS |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2a |
| Applications: | Western Blot (1:450-1:2000); Immunohistochemistry(1:40-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (E10-4B) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Eczema thrombocytopenia antibody |
| IMD2 antibody | |
| SCNX antibody | |
| THC antibody | |
| THC1 antibody | |
| Thrombocytopenia 1 (X linked) antibody | |
| U42471 antibody | |
| Was antibody | |
| WASp antibody | |
| WASP_HUMAN antibody | |
| Wiskott Aldrich syndrome (eczema thrombocytopenia) antibody | |
| Wiskott Aldrich syndrome antibody | |
| Wiskott Aldrich syndrome protein antibody | |
| Wiskott-Aldrich syndrome protein antibody |
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Target information
Effector protein for Rho-type GTPases that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria . In addition to its role in the cytoplasmic cytoskeleton, also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA . Promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs)
Provider
Erpantech Laboratory