Anti-TSG101 antibody
Specifications
| Product Cat#: | AB-06-4472 |
| Product type: | Primary antibody |
| Antigen: | TSG101 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:80-1:500); Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JJ0900) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ESCRT I complex subunit TSG101 antibody |
| ESCRT-I complex subunit TSG101 antibody | |
| TS101_HUMAN antibody | |
| TSG 10 antibody | |
| TSG 101 antibody | |
| TSG10 antibody | |
| Tsg101 antibody | |
| Tumor susceptibility gene 10 antibody | |
| Tumor susceptibility gene 101 antibody | |
| Tumor susceptibility gene 101 protein antibody | |
| Tumor susceptibility protein antibody | |
| Tumor susceptibility protein isoform 3 antibody | |
| VPS 23 antibody | |
| VPS23 antibody |
Target information
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan. It may also play a role in the extracellular release of microvesicles that differ from the exosomes.
Provider
Erpantech Laboratory
