Anti-TRIM25 antibody
Specifications
| Product Cat#: | AB-06-4449 |
| Product type: | Primary antibody |
| Antigen: | TRIM25 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:150-1:500); Flow Cytometry (1:80-1:200); Immunocytochemistry (1:40-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (B12-B5) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | E3 ubiquitin/ISG15 ligase TRIM25 antibody |
| EFP antibody | |
| Estrogen responsive finger protein antibody | |
| Estrogen-responsive finger protein antibody | |
| RING finger protein 147 antibody | |
| RNF 147 antibody | |
| RNF147 antibody | |
| TRI25 antibody | |
| TRI25_HUMAN antibody | |
| TRIM 25 antibody | |
| Trim25 antibody | |
| Tripartite motif containing 25 antibody | |
| Tripartite motif containing protein 25 antibody | |
| Tripartite motif protein TRIM25 antibody | |
| Tripartite motif-containing protein 25 antibody | |
| Tripartite motifcontaining25 antibody | |
| Ubiquitin/ISG15-conjugating enzyme TRIM25 antibody | |
| Z147 antibody | |
| Zinc finger protein 147 (estrogen responsive finger protein) antibody | |
| Zinc finger protein 147 antibody | |
| Zinc finger protein-147 antibody | |
| ZNF 147 antibody | |
| ZNF147 antibody |
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Target information
Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58 and IFIH1. Mediates ‘Lys-63’-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Mediates ‘Lys-63’-linked polyubiquitination of IFIH1. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3.
Provider
Erpantech Laboratory