Anti-HP1 Alpha antibody
Specifications
| Product Cat#: | AB-06-2245 |
| Product type: | Primary antibody |
| Antigen: | HP1 alpha |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1500-1:5000); Immunohistochemistry (1:60-1:200); Immunocytochemistry (1:60-1:200); Flow Cytometry (1:40-1:100);Immunoprecipitation; Immunofluorescence |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal （SR44-03） |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Antigen p25 antibody |
| CBX5 antibody | |
| CBX5_HUMAN antibody | |
| CG8409 antibody | |
| Chromobox 5 antibody | |
| Chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody | |
| Chromobox homolog 5 antibody | |
| Chromobox protein homolog 5 antibody | |
| Epididymis luminal protein 25 antibody | |
| HEL25 antibody | |
| Heterochromatin protein 1 alpha antibody | |
| Heterochromatin protein 1 antibody | |
| Heterochromatin protein 1 homolog alpha antibody | |
| HP1 alpha antibody | |
| HP1 alpha homolog antibody | |
| HP1 antibody | |
| HP1A antibody | |
| HP1Hs alpha antibody | |
| Su(var)205 antibody |
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Target information
Component of heterochromatin that recognizes and binds histone H3 tails methylated at ‘Lys-9’ (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when ‘Tyr-41’ of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Provider
Erpantech Laboratory