Anti-IREB2 Antibody
Specifications
| Product Cat#: | AB-06-2502 |
| Product type: | Primary antibody |
| Antigen: | IREB2 |
| Immunogen: | Full-length recombinant IRP-2 of human origin. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:800-1:2000); Immunoprecipitation; Immunofluorescence( 1:20-1:500 ); Immunohistochemistry-Paraffin (1:500-800) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal(1G3) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ACO3 antibody |
| FLJ23381 antibody | |
| IRE BP2 antibody | |
| IRE-BP 2 antibody | |
| IREB 2 antibody | |
| IREB2 antibody | |
| IREB2_HUMAN antibody | |
| Iron regulatory protein 2 antibody | |
| iron responsive element binding protein 2 antibody | |
| Iron-responsive element-binding protein 2 antibody | |
| IRP 2 antibody | |
| IRP2 antibody | |
| IRP2AD antibody | |
| OTTHUMP00000185022 antibody |
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Target information
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5′-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3′-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Provider
Erpantech Laboratory