Anti-TNNI2 antibody
Specifications
| Product Cat#: | AB-06-4404 |
| Product type: | Primary antibody |
| Antigen: | TNNI2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:50-1:200); Flow Cytometry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (A8-F12) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AMCD 2B antibody |
| AMCD2B antibody | |
| DA 2B antibody | |
| DA2B antibody | |
| Fast skeletal muscle antibody | |
| Fast twitch skeletal muscle troponin I antibody | |
| Fast-twitch isoform antibody | |
| FSSV antibody | |
| FsTnI antibody | |
| TNNI 2 antibody | |
| Tnni2 antibody | |
| TNNI2_HUMAN antibody | |
| Tro antibody | |
| Troponin I antibody | |
| Troponin I fast skeletal muscle antibody | |
| Troponin I fast twitch 2 antibody | |
| Troponin I fast twitch isoform antibody | |
| Troponin I fast twitch skeletal muscle isoform antibody | |
| Troponin I skeletal fast antibody | |
| Troponin I type 2 (skeletal fast) antibody | |
| Troponin I type 2 antibody |
Target information
Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of 2 heavy chains (MHC) and 4 light chains (MLC) that interacts with actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between actin and myosin by binding to calcium. Troponin is made up of at least two subunits, which are skeletal muscle skeletal muscle and slow skeletal muscle. Structures of skeletal muscle troponin are composed of Troponin C (the sensor), Troponin I (the regulator), and Troponin T (the link to the the regulator), and Troponin T C is dumbbell-shaped and has a hydrophobic pocket that increases the contractile force of muscle fibers. Troponin C has 2 isoforms: fast and slow. Fast troponin C has two calci um binding sites while slow / cardiac troponin C has a single calcium binding site.
Provider
Erpantech Laboratory