Anti-TNF Receptor II antibody
Specifications
| Product Cat#: | AB-06-4391 |
| Product type: | Primary antibody |
| Antigen: | TNF Receptor II |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200); Immunoprecipitation(1:20-1:50); Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JM113-01) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD120b antibody |
| P75 antibody | |
| P75 TNF receptor antibody | |
| P75TNFR antibody | |
| P80 TNF alpha receptor antibody | |
| P80 TNF-alpha receptor antibody | |
| Soluble TNFR1B variant 1 antibody | |
| TBP-2 antibody | |
| TBPII antibody | |
| TNF R II antibody | |
| TNF R2 antibody | |
| TNF R75 antibody | |
| TNF-R2 antibody | |
| TNF-RII antibody | |
| TNFBR antibody | |
| TNFR-II antibody | |
| TNFR1B antibody | |
| TNFR2 antibody | |
| TNFR80 antibody | |
| TNFRII antibody | |
| Tnfrsf1b antibody | |
| TNR1B_HUMAN antibody | |
| Tumor necrosis factor beta receptor antibody | |
| Tumor necrosis factor receptor 2 antibody | |
| Tumor necrosis factor receptor superfamily member 1B antibody | |
| Tumor necrosis factor receptor type II antibody | |
| Tumor necrosis factor-binding protein 2 antibody |
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Target information
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Provider
Erpantech Laboratory