Anti-RNF40 antibody
Specifications
| Product Cat#: | AB-06-3900 |
| Product type: | Primary antibody |
| Antigen: | RNF40 |
| Immunogen: | Recombinant protein within human RNF40 aa 200-400 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunoprecipitation (1:10-1:50); Immunohistochemistry (1:50) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JE46-30) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | 95 kDa retinoblastoma associated protein antibody |
| 95 kDa retinoblastoma protein binding protein antibody | |
| 95 kDa retinoblastoma-associated protein antibody | |
| BRE 1B antibody | |
| BRE1 B antibody | |
| BRE1 E3 ubiquitin ligase homolog B antibody | |
| BRE1-B antibody | |
| BRE1B antibody | |
| BRE1B_HUMAN antibody | |
| DKFZp686K191 antibody | |
| E3 ubiquitin protein ligase BRE1B antibody | |
| E3 ubiquitin-protein ligase BRE1B antibody | |
| KIAA0661 antibody | |
| MGC13051 antibody | |
| Rb associated protein antibody | |
| RBP 95 antibody | |
| RBP95 antibody | |
| RING finger protein 40 antibody | |
| Ring finger protein 40 E3 ubiquitin protein ligase antibody | |
| RNF 40 antibody | |
| Rnf40 antibody |
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Target information
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of ‘Lys-120’ of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 ‘Lys-4’ and ‘Lys-79’ methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.
Provider
Erpantech Laboratory