Anti-Alpha-1-antitrypsin antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Alpha-1-antitrypsin |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:5000); Immunoprecipitation; Immunocytochemistry/Immunofluorescence (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, JF10-03 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | A1A antibody |
| A1AT antibody | |
| A1AT_HUMAN antibody | |
| AAT antibody | |
| Alpha 1 antiproteinase antibody |
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Target information
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
Provider
Erpantech Laboratory
