Anti-Integrin Alpha 3 Antibody
Specifications
| Product Cat#: | AB-06-2467 |
| Product type: | Primary antibody |
| Antigen: | Integrin alpha 3 |
| Immunogen: | KLH conjugated synthetic peptide derived from human Integrin alpha 3 light chain 976-1025/1051 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Flow Cytometry (1:80-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Integrin alpha 3 light chain |
| AA407068 | |
| Antigen identified by monoclonal | |
| Integrin alpha-3 | |
| J143 | |
| CD49 antigen like family member C | |
| CD49 antigen-like family member C | |
| CD49c | |
| CD49c antigen | |
| FLJ34631 | |
| FLJ34704 | |
| FRP 2 | |
| FRP-2 | |
| FRP2 | |
| Galactoprotein B3 | |
| GAP B3 | |
| GAPB3 | |
| Integrin alpha 3 | |
| Integrin alpha-3 light chain | |
| Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | |
| ITA3_HUMAN | |
| ITGA 3 | |
| Itga3 | |
| MSK18 | |
| VCA 2 | |
| VCA2 | |
| Very late activation protein 3 receptor alpha 3 subunit | |
| VL3A | |
| VLA 3 alpha chain | |
| VLA 3 subunit alpha | |
| VLA-3 subunit alpha | |
| VLA3a. |
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Target information
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Provider
Erpantech Laboratory