Anti-FUS/TLS antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | FUS/TLS |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:950); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JJ09-31) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 75 kDa DNA pairing protein antibody |
| 75 kDa DNA-pairing protein antibody | |
| ALS6 antibody | |
| Amyotrophic lateral sclerosis 6 antibody | |
| Fus antibody | |
| FUS CHOP antibody | |
| Fus like protein antibody | |
| FUS_HUMAN antibody | |
| FUS1 antibody | |
| Fused in sarcoma antibody | |
| Fusion (involved in t(12;16) in malignant liposarcoma) antibody | |
| Fusion derived from t(12;16) malignant liposarcoma antibody | |
| Fusion gene in myxoid liposarcoma antibody | |
| Heterogeneous nuclear ribonucleoprotein P2 antibody | |
| HnRNP P2 antibody | |
| HnRNPP2 antibody | |
| Oncogene FUS antibody | |
| Oncogene TLS antibody | |
| POMp75 antibody | |
| RNA binding protein FUS antibody | |
| RNA-binding protein FUS antibody | |
| TLS antibody | |
| TLS CHOP antibody | |
| Translocated in liposarcoma antibody | |
| Translocated in liposarcoma protein antibody |
Target information
DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response.Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing . Binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay . Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis
Provider
Erpantech Laboratory