Anti-TIE-1 antibody
Specifications
| Product Cat#: | AB-06-4355 |
| Product type: | Primary antibody |
| Antigen: | TAB1 |
| Immunogen: | Synthetic peptide within human TIE-1 40-120aa. |
| Species immunized: | Rabbit |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:800-1:5000); Immunocytochemistry (1:40-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 25% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | JKT 14 antibody |
| JTK14 antibody | |
| TIE antibody | |
| Tie1 antibody | |
| TIE1_HUMAN antibody | |
| Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1 antibody | |
| Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains antibody | |
| Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody |
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Target information
The Tie-1 receptor is an endothelial specific cell surface tyrosine kinase that is indispensable for endothelial functions. Human TIE1 cDNA encodes a 1138 amino acid residue precursor protein with a putative signal peptide, an extracellular domain, and a cytoplasmic domain. Human TIE1/Fc, a disulfide linked homodimeric protein, has a calculated molecular mass of approximately 107 kDa. Tie-1 and Tie-2 are receptor tyrosine kinases (RTKs) that are exclusively expressed in endothelial cells and play important roles in endothelial cell biology.
Provider
Erpantech Laboratory