Anti-MKP-3 antibody
Specifications
| Product Cat#: | AB-06-2898 |
| Product type: | Primary antibody |
| Antigen: | MKP-3 |
| Immunogen: | An epitope mapping between amino acids 353-381 at the C-terminus of MKP-3 of human origin |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:100-1:1000); Immunoprecipitation (1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) ); Immunohistochemistry (1:50-1:500); Flow Cytometry (1:50-1:500); Immunohistochemistry-Paraffin |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (3G1) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | Dual specificity phosphatase 6 antibody |
| Dual specificity phosphatase 6 isoform a antibody | |
| Dual specificity protein phosphatase 6 antibody | |
| Dual specificity protein phosphatase PYST1 antibody | |
| DUS6_HUMAN antibody | |
| DUSP 6 antibody | |
| DUSP 6a antibody | |
| Dusp6 antibody | |
| DUSP6a antibody | |
| HH19 antibody | |
| MAP kinase phosphatase 3 antibody | |
| Mitogen activated protein kinase phosphatase 3 antibody | |
| Mitogen-activated protein kinase phosphatase 3 antibody | |
| MKP 3 antibody | |
| MKP-3 antibody | |
| MKP3 antibody | |
| PYST 1 antibody | |
| PYST1 antibody | |
| Serine/threonine specific protein phosphatase antibody |
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Target information
Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity). Promotes cell differentiation by regulating MAPK1/MAPK3 activity and regulating the expression of AP1 transcription factors (PubMed:29043977).
Provider
Erpantech Laboratory