Anti-Hexokinase1 antibody
Specifications
| Product Cat#: | AB-06-2146 |
| Product type: | Primary antibody |
| Antigen: | Hexokinase 1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200); Flow Cytometry (1:40-1:100)；Immunoprecipitation; Immunofluorescence |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (ST47-05） |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BB404130 antibody |
| Brain form hexokinase antibody | |
| Dea antibody | |
| DrHXK1 antibody | |
| EC 2.7.1.1 antibody | |
| Glycolytic enzyme antibody | |
| HEXOKIN antibody | |
| hexokinase I antibody | |
| Hexokinase PI antibody | |
| Hexokinase type I antibody | |
| Hexokinase, tumor isozyme antibody | |
| Hexokinase-1 antibody | |
| Hexokinase-A antibody | |
| HK I antibody | |
| HK1 antibody | |
| HK1 tb antibody | |
| Hk1-s antibody | |
| HK1-ta antibody | |
| HK1-tb antibody | |
| HK1-tc antibody | |
| HKD antibody | |
| HKI antibody | |
| HMSNR antibody | |
| HXK1 antibody | |
| HXK1_HUMAN antibody | |
| Im:7148527 antibody | |
| MHk1-s antibody | |
| Wu:fc09d08 antibody | |
| Wu:fc16e02 antibody | |
| Wu:fc21e02 antibody | |
| Wu:fq14b11 antibody | |
| Zgc:55790 antibody | |
| Zgc:77618 antibody |
Target information
Catalyzes the phosphorylation of various hexoses, such as D-glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6-phosphate, respectively) (PubMed:1637300, PubMed:25316723, PubMed:27374331). Does not phosphorylate N-acetyl-D-glucosamine (PubMed:27374331). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor for bacterial peptidoglycan (PubMed:27374331). When released in the cytosol, N-acetyl-D-glucosamine component of bacterial peptidoglycan inhibits the hexokinase activity of HK1 and causes its dissociation from mitochondrial outer membrane, thereby activating the NLRP3 inflammasome (PubMed:27374331).
Provider
Erpantech Laboratory
