Anti-Hes1 antibody
Specifications
| Product Cat#: | AB-06-2142 |
| Product type: | Primary antibody |
| Antigen: | Hes1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:50-1:500); Immunofluorescence |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (SC06-21） |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | bHLHb39 antibody |
| C-HAIRY1 antibody | |
| Class B basic helix-loop-helix protein 39 antibody | |
| FLJ20408 antibody | |
| Hairy and enhancer of split 1 (Drosophila) antibody | |
| Hairy and enhancer of split 1 antibody | |
| Hairy homolog (Drosophila) antibody | |
| Hairy homolog antibody | |
| Hairy like antibody | |
| Hairy, Drosophila, homolog of antibody | |
| Hairy-like protein antibody | |
| Hairy/enhancer of split, Drosophila, homolog of, 1 antibody | |
| HAIRY1 antibody | |
| HES-1 antibody | |
| Hes1 antibody | |
| Hes1 hairy and enhancer of split 1 (Drosophila) antibody | |
| HES1_HUMAN antibody | |
| HHL antibody | |
| HL antibody | |
| HRY antibody | |
| MGC129109 antibody | |
| OTTHUMP00000209031 antibody | |
| RHL antibody | |
| Transcription factor HES-1 antibody |
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Target information
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5′-CACNAG-3′ with high affinity and on E-box motifs: 5′-CANNTG-3′ with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Provider
Erpantech Laboratory