Anti-RBPMS antibody
Specifications
| Product Cat#: | AB-06-3838 |
| Product type: | Primary antibody |
| Antigen: | RBPMS |
| Immunogen: | Synthetic peptide within human RBPMS 1-30 conjugated to Keyhole Limpet Haemocyanin. |
| Species immunized: | Guinea Pig |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); ELISA (1:1000-1:4000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (pH7.4), 0.2% BSA, 50% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | RNA-binding protein with multiple splicing |
| Heart and RRM expressed sequence |
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Target information
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins (PubMed:26347403). Binds to poly(A) RNA (PubMed:17099224, PubMed:26347403).
Provider
Erpantech Laboratory
