Anti-MEF2C antibody
Specifications
| Product Cat#: | AB-06-2846 |
| Product type: | Primary antibody |
| Antigen: | MEF2C |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (G2-H2) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | C5DELq14.3 antibody |
| DEL5q14.3 antibody | |
| MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C) antibody | |
| MADS box transcription enhancer factor 2, polypeptide C antibody | |
| MEF2C antibody | |
| MEF2C_HUMAN antibody | |
| Myocyte enhancer factor 2C antibody | |
| Myocyte specific enhancer factor 2C antibody | |
| Myocyte-specific enhancer factor 2C antibody | |
| OTTHUMP00000222409 antibody |
Target information
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoforms that lack the repressor domain are more active than isoform 1.
Provider
Erpantech Laboratory
