Anti-MEF2A antibody
Specifications
| Product Cat#: | AB-06-2845 |
| Product type: | Primary antibody |
| Antigen: | MEF2A |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JA33-04) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | ADCAD1 antibody |
| MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody | |
| MEF2 antibody | |
| MEF2A antibody | |
| MEF2A_HUMAN antibody | |
| Myocyte enhancer factor 2A antibody | |
| Myocyte-specific enhancer factor 2A antibody | |
| RSRFC4 antibody | |
| RSRFC9 antibody | |
| Serum response factor like protein 1 antibody |
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Target information
Transcriptional activator which binds specifically to the MEF2 element, 5′-YTA[AT]4TAR-3′, found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Provider
Erpantech Laboratory