Anti-MDR1 antibody
Specifications
| Product Cat#: | AB-06-2841 |
| Product type: | Primary antibody |
| Antigen: | MDR1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human MDR1 21-100/1272 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1μg/Test) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | P-Glycoprotein |
| Multi Drug Resistance Associated Protein, ABCB1 | |
| ATP-binding cassette sub-family B (MDR/TAP), member 1 | |
| ABC20 | |
| CD243 | |
| CD243 antigen | |
| CLCS | |
| Multidrug resistance protein 1 | |
| P glycoprotein 1 | |
| p-GP | |
| gp170 | |
| P gp | |
| PGY1 |
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Target information
Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (By similarity).
Provider
Erpantech Laboratory