Anti-MCT1 antibody
Specifications
| Product Cat#: | AB-06-2834 |
| Product type: | Primary antibody |
| Antigen: | MCT1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human MCT1 251-350/500 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800); Flow Cytometry (1μg/Test) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | Monocarboxylate transporter 1 |
| Malignant T cell amplified sequence 1 | |
| MCT 1 | |
| MCT1 | |
| MCTS 1 | |
| MCTS1 | |
| Oncogene MCT 1 | |
| Oncogene MCT1 | |
| SLC16A1 | |
| FLJ36745 | |
| HHF7 | |
| MCT | |
| MGC44475 | |
| Monocarboxylate transporter | |
| Monocarboxylate transporter isoform 1 | |
| Monocarboxylic acid transporter 1 | |
| SLC16A1 | |
| SLC16A1 protein | |
| Solute carrier family 16 (monocarboxylic acid transporters) member 1 | |
| Solute carrier family 16 member 1 (monocarboxylic acid transporter 1) | |
| Solute carrier family 16 member 1 |
Target information
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.
Provider
Erpantech Laboratory
