Anti-RAD51 antibody
Specifications
| Product Cat#: | AB-06-3806 |
| Product type: | Primary antibody |
| Antigen: | RAD51 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500); Immunohistochemistry (1:50-1:200); Immunofluorescence/Immunocytochemistry (1:50-1:200); Immunohistochemistry (1:50-1:200); Immunoprecipitation (1:10-1:50) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JM54-26) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | BRCA1/BRCA2 containing complex, subunit 5 antibody |
| BRCC 5 antibody | |
| BRCC5 antibody | |
| DNA repair protein RAD51 homolog 1 antibody | |
| DNA repair protein rhp51 antibody | |
| FANCR antibody | |
| hRAD51 antibody | |
| HsRAD51 antibody | |
| HsT16930 antibody | |
| MRMV2 antibody | |
| Rad 51 antibody | |
| RAD51 antibody | |
| RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) antibody | |
| RAD51 homolog A antibody | |
| RAD51 homolog antibody | |
| RAD51 recombinase antibody | |
| RAD51, S. cerevisiae, homolog of antibody | |
| RAD51_HUMAN antibody | |
| RAD51A antibody | |
| RECA antibody | |
| RecA like protein antibody | |
| RecA, E. coli, homolog of antibody | |
| Recombination protein A antibody |
Target information
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed:28575658). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair (PubMed:26253028).
Provider
Erpantech Laboratory
