Anti-Hepcidin antibody
Specifications
| Product Cat#: | AB-06-2136 |
| Product type: | Primary antibody |
| Antigen: | Hepcidin |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:1000); Immunohistochemistry (1:100-1:200) |
| Reactivity: | Rat, Human |
| Clonality (clone number): | Monoclonal (JA11-27) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Hamp antibody |
| HEPC antibody | |
| HEPC_HUMAN antibody | |
| Hepc20 antibody | |
| Hepc25 antibody | |
| Hepcidin-20 antibody | |
| HFE2B antibody | |
| LEAP-1 antibody | |
| LEAP1 antibody | |
| Liver-expressed antimicrobial peptide 1 antibody | |
| PLTR antibody | |
| Putative liver tumor regressor antibody |
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Target information
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes .
Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa .
Provider
Erpantech Laboratory