Anti-Lysyl tRNA Synthetase antibody
Specifications
| Product Cat#: | AB-06-2765 |
| Product type: | Primary antibody |
| Antigen: | Lysyl tRNA Synthetase |
| Immunogen: | Recombinant protein corresponding to C-terminal human Lysyl tRNA synthetase |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:500-1:200); Immunocytochemistry (1:50-1:100); Immunoprecipitation (1:10-1:50) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JE40-55) |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | CMTRIB antibody |
| DFNB89 antibody | |
| EC 6.1.1.6 antibody | |
| KARS 1 antibody | |
| KARS 2 antibody | |
| KARS antibody | |
| KARS1 antibody | |
| KARS2 antibody | |
| KIAA0070 antibody | |
| KRS antibody | |
| Lysine tRNA ligase antibody | |
| LysinetRNA ligase antibody | |
| LysRS antibody | |
| Lysyl-tRNA synthetase antibody | |
| SYK_HUMAN antibody |
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Target information
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:9278442, PubMed:18029264, PubMed:18272479). When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages (PubMed:15851690). Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:5338216, PubMed:14975237, PubMed:19524539, PubMed:23159739).
Provider
Erpantech Laboratory