Anti-LXR Alpha antibody
Specifications
| Product Cat#: | AB-06-2756 |
| Product type: | Primary antibody |
| Antigen: | LXR Alpha |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500); Immunohistochemistry (1:50-1:200); Flow Cytometry (1:50-1:100); Immunocytochemistry |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JA20-38) |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Liver X receptor alpha antibody |
| LXR a antibody | |
| LXRA antibody | |
| NR1H3 antibody | |
| NR1H3_HUMAN antibody | |
| Nuclear receptor subfamily 1 group H member 3 antibody | |
| Oxysterols receptor LXR alpha antibody | |
| Oxysterols receptor LXR-alpha antibody | |
| RLD 1 antibody | |
| RLD1 antibody |
Target information
Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920). Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES (By similarity). LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity). Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).
Provider
Erpantech Laboratory
