Anti-Drosha antibody
Specifications
| Product Cat#: | AB-06-1453 |
| Product type: | Primary antibody |
| Antigen: | Drosha |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:200); Immunocytochemistry (1:100-1:200); Immunofluorescence |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JU33-01) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DROSHA antibody |
| Drosha double stranded RNA specific endoribonuclease antibody | |
| Drosha ribonuclease type III antibody | |
| Etohi2 antibody | |
| HSA242976 antibody | |
| Nuclear RNase III Drosha antibody | |
| P241 antibody | |
| Protein Drosha antibody | |
| Putative protein p241 which interacts with transcription factor Sp1 antibody | |
| Putative ribonuclease III antibody | |
| RANSE3L antibody | |
| Ribonuclease 3 antibody | |
| Ribonuclease III antibody | |
| Ribonuclease III nuclear antibody | |
| Ribonuclease type III nuclear antibody | |
| RibonucleaseIII antibody | |
| RN 3 antibody | |
| RN3 antibody | |
| RNase 3 antibody | |
| RNase III antibody | |
| RNase3 antibody | |
| RNASE3L antibody | |
| RNaseIII antibody | |
| RNASEN antibody | |
| RNC_HUMAN antibody |
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Target information
Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3′ and 5′ strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
Provider
Erpantech Laboratory
