Anti-IL12B antibody
Specifications
| Product Cat#: | AB-06-2390 |
| Product type: | Primary antibody |
| Antigen: | IL12B |
| Immunogen: | Synthetic peptide within mouse IL12B 220-300 aa. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 0.5% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CLMF antibody |
| CLMF p40 antibody | |
| CLMF2 antibody | |
| Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody | |
| IL 12B antibody | |
| IL-12 subunit p40 antibody | |
| IL-12B antibody | |
| IL12 p40 antibody | |
| IL12B antibody | |
| IL12B_HUMAN antibody | |
| IMD28 antibody | |
| IMD29 antibody | |
| Interleukin 12 beta chain antibody | |
| Interleukin 12 p40 antibody | |
| Interleukin-12 subunit beta antibody | |
| NK cell stimulatory factor chain 2 antibody | |
| NKSF antibody | |
| NKSF2 antibody |
Target information
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Provider
Erpantech Laboratory
