Anti-KLHL21 antibody
Specifications
| Product Cat#: | AB-06-2628 |
| Product type: | Primary antibody |
| Antigen: | KLHL21 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (F4-H4) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Kelch-Like Protein 21 antibody |
| KIAA0469 antibody | |
| KLH21_HUMAN antibody | |
| KLHL21 antibody | |
| MGC99635 antibody |
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Target information
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
Provider
Erpantech Laboratory