Anti-IKK Gamma antibody
Specifications
| Product Cat#: | AB-06-2383 |
| Product type: | Primary antibody |
| Antigen: | IKK gamma |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:10-1:80); Immunocytochemistry (1:80-1:200); Immunofluorescence; Immunoprecipitation; Flow Cytometry (1:100-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (JA11-83) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | IkB kinase associated protein 1 antibody |
| IkB kinase subunit gamma antibody | |
| Inhibitor of nuclear factor kappa B kinase subunit gamma antibody | |
| AMCBX1 antibody | |
| FIP 3 antibody | |
| FIP-3 antibody | |
| FIP3 antibody | |
| Fip3p antibody | |
| I kappa B kinase gamma antibody | |
| I-kappa-B kinase subunit gamma antibody | |
| IkB kinase gamma subunit antibody | |
| IkB kinase subunit gamma antibody | |
| IkB kinase-associated protein 1 antibody | |
| Ikbkg antibody | |
| IKK-gamma antibody | |
| IKKAP1 antibody | |
| IKKG antibody | |
| IMD33 antibody | |
| Incontinentia pigmenti antibody | |
| Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma antibody | |
| Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma antibody | |
| Inhibitor of nuclear factor kappa-B kinase subunit gamma antibody | |
| IP antibody | |
| IP1 antibody | |
| IP2 antibody | |
| IPD2 antibody | |
| NEMO antibody | |
| NEMO_HUMAN antibody | |
| NF kappa B essential modifier antibody | |
| NF kappa B essential modulator antibody | |
| NF-kappa-B essential modifier antibody |
Target information
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either ‘Lys-63’-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires ‘Lys-27’-linked polyubiquitination.
Provider
Erpantech Laboratory