Anti-DNA Ligase IV antibody
Specifications
| Product Cat#: | AB-06-1403 |
| Product type: | Primary antibody |
| Antigen: | DNA Ligase IV |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:20-1:50) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JM64-32) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH 7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DNA ligase IV ATP dependent antibody |
| DNA joinase antibody | |
| DNA ligase 4 antibody | |
| DNA ligase IV antibody | |
| DNA repair enzyme antibody | |
| DNLI4_HUMAN antibody | |
| LIG 4 antibody | |
| LIG4 antibody | |
| LIG4S antibody | |
| Ligase IV antibody | |
| Ligase IV DNA ATP dependent antibody | |
| Polydeoxyribonucleotide synthase [ATP] 4 antibody | |
| Polydeoxyribonucleotide synthase 4 antibody | |
| Polydeoxyribonucleotide synthase antibody | |
| Polynucleotide ligase antibody | |
| Sealase antibody |
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Target information
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Provider
Erpantech Laboratory
