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Anti-GluR2 antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-1939
Anti-GluR2 antibody
Erpan Tech In stock

Specifications        

Product Cat#: AB-06-1939
Product type: Primary antibody
Antigen: GluR2
Immunogen: Recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:500); Immunocytochemistry (1:50-1:200); Immunohistochemistry (1:50-1:200); Immunofluorescence; Immunoprecipitation
Reactivity: Human, Mouse, Rat
Clonality (clone number): Monoclonal (JU20-43)
Form: Liquid
Buffer: 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Alternative names: AMPA 2 antibody
AMPA selective glutamate receptor 2 antibody
AMPA-selective glutamate receptor 2 antibody
AMPA2 antibody
GluA2 antibody
GLUR 2 antibody
GLUR B antibody
GluR K2 antibody
GluR-2 antibody
GluR-B antibody
GluR-K2 antibody
GLUR2 antibody
GLURB antibody
Glutamate receptor 2 antibody
Glutamate receptor ionotropic AMPA 2 antibody
Glutamate receptor ionotropic antibody
Gria2 antibody
GRIA2_HUMAN antibody
HBGR2 antibody
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Target information

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).

Provider

Erpantech Laboratory

download

MSDS-AB-06-1939.pdf (119 downloads)