Anti-UFD1L antibody
Specifications
| Product Cat#: | AB-06-4891 |
| Product type: | Primary antibody |
| Antigen: | UFD1L |
| Immunogen: | Synthetic peptide within human UFD1L aa 11-60/307. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal, JE64-80 |
| Form: | Liquid |
| Buffer: | 1*TBS buffer (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | UB fusion protein 1 antibody |
| Ubiquitin fusion degradation 1 like (yeast) antibody | |
| Ubiquitin fusion degradation 1 like antibody | |
| Ubiquitin fusion degradation protein 1 homolog antibody | |
| UFD1 antibody | |
| UFD1_HUMAN antibody | |
| UFD1L antibody |
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Target information
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Provider
Erpantech Laboratory
