Anti-MRPL45 antibody
Specifications
| Product Cat#: | AB-08-0096 |
| Product type: | Primary antibody |
| Antigen: | MRPL45 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 57-306 of human MRPL45 (NP_115727.5). |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunofluorescence (1:40-1:200); Immunohistochemistry-Paraffin (1:40-200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality: | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.3), 50% Glycerol, 0.02% NaN3. |
| Purity: | Immoungen affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | LHPP; HDHD2B |
Target information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
Provider
Erpantech Laboratory
