Anti-GSDMD antibody
Specifications
| Product Cat#: | AB-08-0088 |
| Product type: | Primary antibody |
| Antigen: | GSDMD |
| Immunogen: | Recombinant protein of human GSDMD. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunofluorescence (1:40-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality: | Monoclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.3), 50% Glycerol, 0.5% BSA, 0.02% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Non-conjugated |
| Alternative names: | DF5L; DFNA5L; FKSG10; GSDMDC1; GSDMD |
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Target information
Gasdermin-D:
Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27281216).
This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:26375003, PubMed:26375259, PubMed:27281216).
Provider
Erpantech Laboratory
