Anti-IFNAR1 antibody
Specifications
| Product Cat#: | AB-06-2346 |
| Product type: | Primary antibody |
| Antigen: | IFNAR1 |
| Immunogen: | Recombinant protein within human IFNAR1 aa 28-127 (Extracellular). |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500); Immunohistochemistry-Paraffin (1:100-200); Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal, A5-A3 |
| Form: | Liquid |
| Buffer: | 1*PBS (pH7.4), 0.2% BSA, 50% glycerol and 0.05% sodium azide. |
| Concentration: | 2 mg/ml |
| Purity: | Protein G affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Non-conjugated |
| Alternative names: | Alpha type antiviral protein antibody |
| Antiviral protein, alpha-type antibody | |
| Antiviral protein, beta-type antibody | |
| AVP antibody | |
| Beta type antiviral protein antibody | |
| CRF2-1 antibody | |
| Cytokine receptor class-II member 1 antibody | |
| Cytokine receptor family 2 member 1 antibody | |
| IFN alpha REC antibody | |
| IFN alpha receptor antibody | |
| IFN alpha/beta Receptor alpha antibody | |
| IFN beta receptor antibody | |
| IFN Interferon-beta receptor antibody | |
| IFN-alpha/beta receptor 1 antibody | |
| IFN-R-1 antibody | |
| IFNAR antibody | |
| Ifnar1 antibody | |
| IFNBR antibody | |
| IFRC antibody | |
| INAR1_HUMAN antibody | |
| Interferon (alpha beta and omega) receptor 1 antibody | |
| interferon alpha and beta receptor subunit 1 antibody | |
| Interferon alpha/beta receptor 1 antibody | |
| Interferon alpha/beta receptor alpha chain antibody | |
| Interferon beta receptor 1 antibody | |
| interferon receptor 1 antibody | |
| Interferon-alpha receptor antibody | |
| Type I interferon receptor 1 antibody |
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Target information
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986).
Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986).
Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986, PubMed:32972995).
Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).
Provider
Erpantech Laboratory
