Anti-GFRAL antibody
Specifications
| Product Cat#: | AB-06-1899 |
| Product type: | Primary antibody |
| Antigen: | GFRAL |
| Immunogen: | KLH conjugated synthetic peptide derived from human GFRAL 151-250/394 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | GDNF family receptor alpha-like |
| Gfral | |
| GFRAL_HUMAN | |
| UNQ9356/PRO34128 | |
| UNQ9356 | |
| bA360D14.1 |
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Target information
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Provider
Erpantech Laboratory
