Anti-GADD45GIP1 antibody
Specifications
| Product Cat#: | AB-07-0534 |
| Product type: | Primary antibody |
| Antigen: | GADD45GIP1 |
| Immunogen: | A synthetic peptide derived from human GADD45GIP1 . The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry: 1:50~1:100 ELISA: 1:40000 |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | GADD45GIP1 ;Growth arrest and DNA-damage-inducible proteins-interacting protein 1; CR6-interacting factor 1; CRIF1; CKII beta-associating protein; Papillomavirus L2-interacting nuclear protein 1; PLINP-1; p53-responsive gene 6 protein |
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Target information
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Provider
Erpantech Laboratory
