Anti-EMR3 antibody
Specifications
| Product Cat#: | AB-07-0477 |
| Product type: | Primary antibody |
| Antigen: | EMR3 |
| Immunogen: | A synthetic peptide derived from human EMR3 . The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot: 1:500~1:3000 ELISA: 1:10000 |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | EMR3 /EGF-like module-containing mucin-like hormone receptor-like 3 [Precursor]; EGF-like module-containing mucin-like hormone receptor-like 3 [Precursor]; EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha; EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta; EMR3; UNQ683/PRO1562 |
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Target information
Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242).
Provider
Erpantech Laboratory
