Anti-CLTR1 antibody
Specifications
| Product Cat#: | AB-07-0339 |
| Product type: | Primary antibody |
| Antigen: | CLTR1 |
| Immunogen: | A synthetic peptide derived from human CLTR1. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:10000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CLTR1; CYSLT1; CYSLT1R; CYSLTR; Cysteinyl leukotriene D4 receptor; Cysteinyl leukotriene receptor 1; HG55; HMTMF81; LTD4 receptor |
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Target information
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Provider
Erpantech Laboratory
