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Anti-14-3-3 Beta/Alpha antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-0080
Anti-14-3-3 Beta/Alpha antibody
Erpan Tech In stock

Specifications        

Product Cat#: AB-06-0080
Product type: Primary antibody
Antigen: 14-3-3 Beta/Alpha
Immunogen: Peptide
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:2000-4000); Immunocytochemistry (1:1:100-1:200); Immunohistochemistry-Paraffin
Reactivity: Mouse, Rat and Human
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 0.2% BSA, 40% glycerol, 0.05% NaN3.
Concentration: 1 mg/ml
Purity: Immunogen affinity purified.
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: 14 3 3 alpha antibody
14 3 3 protein beta/alpha antibody
14-3-3 protein beta/alpha antibody
1433B_HUMAN antibody
Brain protein 14 3 3 beta isoform antibody
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Target information

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.

Provider

Erpantech Laboratory

download

MSDS-AB-06-0080.pdf (381 downloads )