Anti-GSPT1 antibody
Specifications
| Product Cat#: | AB-07-2956 |
| Product type: | Primary antibody |
| Antigen: | GSPT1 |
| Immunogen: | A synthetic peptide derived from human GSPT1. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry (1:50-1:100); ELISA (1:40000) |
| Reactivity: | Mouse, Human, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | G1 to S phase transition protein 1 homolog, GTP-binding protein GST1-HS, GSPT1 |
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Target information
Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activity of ETF1 (By similarity). Involved in regulation of mammalian cell growth (PubMed:2511002). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:24486019). Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes (PubMed:30682371).
Provider
Erpantech Laboratory
