Anti-GPR44 antibody
Specifications
| Product Cat#: | AB-06-2009 |
| Product type: | Primary antibody |
| Antigen: | GPR44 |
| Immunogen: | KLH conjugated synthetic peptide derived from human GPR44/CD294 121-220/395 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | GPCR GPR44 |
| CD294 | |
| CD 294 | |
| CD294 antigen | |
| Chemoattractant receptor homologous molecule expressed on Th2 cells | |
| chemoattractant receptor-homologous | |
| Chemoattractant receptor-homologous molecule expressed on Th2 cells | |
| CRTH 2 | |
| CRTH2 | |
| DL1R | |
| DP2 prostaglandin receptor | |
| G Protein Coupled Receptor 44 | |
| GPR 44 | |
| Gpr44 | |
| PD2R2_HUMAN | |
| PTGDR2 |
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Target information
Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
Provider
Erpantech Laboratory