Anti-Noxa antibody
Specifications
| Product Cat#: | AB-06-3181 |
| Product type: | Primary antibody |
| Antigen: | Noxa |
| Immunogen: | KLH conjugated synthetic peptide derived from human NOX5 675-765/765 |
| Species immunized: | Rabbit |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500);Immunohistochemistry(1:100-1:200); Flow Cytometry (1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Adult T cell leukemia derived PMA responsive antibody |
| APR antibody | |
| APR_HUMAN antibody | |
| ATL-derived antibody | |
| Immediate early response protein APR antibody | |
| Immediate-early-response protein APR antibody | |
| NOXA antibody | |
| Phorbol 12 myristate 13 acetate induced protein 1 antibody | |
| Phorbol-12-myristate-13-acetate-induced protein 1 antibody | |
| PMA induced protein 1 antibody | |
| PMA-induced protein 1 antibody | |
| PMA-responsive gene antibody | |
| Pmaip1 antibody | |
| Protein Noxa antibody |
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Target information
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Provider
Erpantech Laboratory